Blood pH


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Blood pH
Blood pHThe pH of normal healthy blood is in the range of 7.35 to 7.45. When the pH is less than 7.35, this condition is defined as acidosis. When the pH is greater than 7.45, this condition is defined as alkalosis. CO2 dissolved in water in plasma produces carbonic acid, which lowers blood pH. Bicarbonate and carbonic acid form an acid–base buffer pair, which helps to keep the arterial pH near 7.4. When PCO2 decreases, then the pH increases.The ratio of bicarbonate concentration to partial pressure of CO2 in blood is a ratio of metabolic compensation to respiratory compensation. The Henderson–Hasselbalch equation can be used to calculate the pH of arterial blood based on that ratio.
Citation
Lee Waite, Ph.D., P.E.; Jerry Fine, Ph.D.: Applied Biofluid Mechanics, Second Edition. Blood pH, Chapter (McGraw-Hill Professional, 2017), AccessEngineering Export