Renin-Angiotensin-Aldosterone System


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Renin-Angiotensin-Aldosterone System
Renin-Angiotensin-Aldosterone SystemRenin is a protein and enzyme produced in the kidneys and secreted from the juxtaglomerular apparatus in response to the following three stimuli: Decreased arterial pressure Decreased sodium load delivered to the distal tubule Sympathetic nervous system activity Renin circulates in the blood stream and breaks down angiotensinogen to angiotensin I. Angiotensin I is cleaved by angiotensin converting enzyme (ACE) into angiotensin II, a potent constructor of blood vessels. The constriction of arteries and arterioles by angiot…
Citation
Lee Waite, Ph.D., P.E.; Jerry Fine, Ph.D.: Applied Biofluid Mechanics, Second Edition. Renin-Angiotensin-Aldosterone System, Chapter (McGraw-Hill Professional, 2017), AccessEngineering Export