Unstructured PBMs


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Unstructured PBMs
1010103Unstructured PBMsUnstructured population balance models use a single variable, such as cell mass, to indicate the state of a cell in the culture. Unstructured models are the least complex PBMs, and will be explored in this and the following chapters. We will derive a general population balance model that uses cell mass or any other variable that is conserved in a cell division, together with associated substrate and product balances. The age population balance is also rederived together with the boundary conditions that are specific to cell age as the cell state parameter.
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Citation
Martin A. Hjortsø: Population Balances in Biomedical Engineering: Segregation through the Distribution of Cell States. Unstructured PBMs, Chapter (McGraw-Hill Professional, 2006), AccessEngineering Export